教学内容
      药剂学I
     药剂学III
     考试考核办法
 
 
  教学内容——药剂学I
 

  

  按教学大纲的安排,药剂学Ⅰ主要介绍药剂学的传统剂型。共60 学时,其中讲课 36 学时,实验 24学时。具体的教学内容安排如下:

药剂学Ⅰ理论课部分知识模块顺序和对应的学时


章节

讲 课 内 容

学时

药剂学的概念与任务,药剂学的分支学科,药物剂型概论,辅料在药物制剂中的应用,药典与药品标准,GMP与GLP,药剂学的沿革与发展等。
Chapter 1: Introduction including definition and tasks of pharmaceutics, the branch subjects, dosage forms, functions of excipients in pharmaceutics, pharmacopoeia, GMP and GLP…

2

液体药剂概论,常用溶剂及附加剂,低分子溶液剂、高分子溶液剂
Chapter 2: Liquid dosage forms including commonly used solvents and excipients, low molecular weight solutions, polymer solutions

2

混悬剂的基本要求、物理稳定性、稳定化方法、制备方法、常用设备及质量评定
Chapter 2: Suspension including physical stability, methods of preparation, commonly used apparatus and quality evaluation

2

乳剂的组成、类型、特点,乳剂的乳化剂、稳定性、制备方法、常用设备及质量评定,复乳
Chapter 2: Emulsions including composition, type, properties, emulsifiers, stability, preparation method and quality evaluation

2

注射剂的定义、分类、特点、给药途径及质量要求,注射剂的溶剂与附加剂,注射用水及热原
Chapter 3: Injections including definition, properties, solvents and excipients, water for injection and pyrogen related contents

2

注射剂的制备(配制、过滤、灌封、灭菌、检漏、质检、印字和包装),举例,输液概述
Chapter 3: Injections including procedures of preparation, introduction of infusion

2

注射用无菌粉末,冷冻干燥原理,注射剂新产品试制和质量研究、眼用制剂
Chapter 3: Injections including sterile powder for injection, freeze dried powder, R&D of injection and ophthalmic preparations

2

固体制剂概述,散剂
Chapter 4: Solid dosage forms introduction and powder

2

片剂的概述,片剂的常用辅料
Chapter 4: Tablets including introduction, commonly used excipients

2

片剂的制备方法和常见问题分析
Chapter 4: Tablet preparation methods

2

片剂的包衣、质量检查及包装
Chapter 4: Tablets coating and quality control

2

颗粒剂,滴丸剂
Chapter 4: granules, pills

2

胶囊剂(硬胶囊剂、软胶囊剂),滴丸的概述、基质、制备工艺与设备
Chapter 4: Capsules including hard capsules and soft capsules

2

软膏剂的概述、基质与添加剂,油膏剂,乳膏剂,凝胶剂,糊剂,眼膏剂,质量检查
Chapter 5: Ointments based on different kinds of bases, ophthalmic ointments

2

油膏剂,乳膏剂,凝胶剂,糊剂,眼膏剂,质量检查
Chapter 5: Ointments formulation design, quality control

2

栓剂的概述、制备方法及设备、治疗作用及质量评价,膜剂的概述、成膜材料及制备工艺
Chapter 5: Suppository and films including formulation composition and preparation methods

2

气雾剂概述、组成、制备、质量评价、喷雾剂、粉雾剂
Chapter 6: Aerosols and sprays

2

浸出制剂概述、常用浸出制剂及设备、质量控制
Chapter 7: Extractions including extraction methods and suitability

2

总计

 

36

药剂学Ⅰ实验课部分的内容和对应的学时


实验

实验内容

学时

混悬剂的制备
Preparation of suspensions and selection of stabilizers

4

Vc注射剂的制备
Preparation and evaluation of 5% Vc injection

4

乳剂的制备
Preparation of emulsions

4

软膏的制备及基质对药物释放的影响
Preparation and evaluation of the effect of ointment bases on in vitro drug release

4

栓剂制备
Preparation of suppositories and determination of displacement value

4

片剂的制备
Preparation of tablets and factors influencing tablets qualities

4

总计

 

24